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Público·6 miembros
Jeremiah Torres
Jeremiah Torres

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The long term aim of our approach is to develop a specific Oncosimulator [45] based on a clinically adapted and validated multiscale model of vascular tumour growth and response to treatment. Certain models that have appeared in literature rely on preliminary validation based mostly on logical and mathematical tests and gross qualitative observations of experimental and/or clinical reality. Some other models, including the present work as well as previous work of our group [28, 46], also attempt a quantitative fitting to sets of experimental and clinical data [31, 44, 47]. Motivation to develop the present model has been provided by the large-scale European Commission funded project p-Medicine. Within the framework of this project, Oncosimulators [45] for the optimal personalized treatment of breast cancer patients treated with bevacizumab had to be developed.

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